As part of our social commitment, we at the EY-Parthenon Business Circle proudly support Humane World for Animals, an NPO that is leading a transformative movement to modernize biomedical research by championing animal-free, human-centered science. Biomedical research is stuck in a rut. Despite billions in investment and cutting-edge facilities, up to 95% of new drugs fail in clinical trials. The reason? Animal experiments long considered the gold standard too often fail to predict how humans will respond. What was once seen as indispensable is now one of the greatest obstacles to medical progress.
A bold vision for the future
Humane World for Animals is determined to change this with a bold vision: research that focuses on human biology rather than animal models. The future lies in powerful new technologies such as organ-on-a-chip systems that mimic human organs, 3D cell cultures and advanced computer modeling. These methods are not only more ethical, they are also more accurate. A human liver-on-a-chip, for example, has already outperformed animal tests in predicting drug-induced liver injury.
Adopting animal-free research requires systemic change
To make this shift possible, research funding must be redirected, policies updated and scientists trained in human-centered methods. That’s the mission of the BioMed21 Collaboration, a global network that brings together researchers, non-animal method developers and policymakers. In workshops from Europe to Brazil, India and South Africa, they are tackling the big questions: How can we move beyond animal models? What policy and funding structures are needed? And how can innovative methods be integrated into labs more quickly?
In essence, this is about more than just science, it’s about a cultural shift. For decades, animal models have dominated biomedical research. Humane World for Animals challenges long-held assumptions, demanding scientific proof of their value and working with partners to develop ambitious projects and policies.
A healthier and more humane tomorrow
The vision is ambitious but within reach: a research system that delivers faster, more effective therapies for people while sparing countless animals from suffering. Modern science has the power to make medicine more precise, efficient and humane as long as we are willing to let go of outdated practices.
The message is clear: “The future of medical progress depends on animal-free research.” Humane World for Animals is showing the way forward and inviting scientists, policymakers and society to be part of this historic shift.
